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PKLR 抗体 (AA 510-550)

This 兔 多克隆 antibody specifically detects PKLR in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8124185
发货至: 中国
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Quick Overview for PKLR 抗体 (AA 510-550) (ABIN8124185)

抗原

See all PKLR 抗体
PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

适用

  • 72
  • 42
  • 32
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 9
兔

克隆类型

  • 72
  • 7
多克隆

标记

  • 37
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This PKLR antibody is un-conjugated

应用范围

  • 45
  • 32
  • 31
  • 10
  • 8
  • 5
  • 5
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 14
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-550

    原理

    KPYR Antibody

    特异性

    KPYR Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein at AA range: 510-550

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

    别名

    KPYR

    背景

    Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: PKLR PK1 PKL

    Protein Name: Pyruvate kinase isozymes R/L (EC 2.7.1.40) (Pyruvate kinase 1) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase)

    基因ID

    5313

    UniProt

    P30613

    途径

    Ribonucleoside Biosynthetic Process
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