PKLR 抗体 (AA 510-550)
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Quick Overview for PKLR 抗体 (AA 510-550) (ABIN8124185)
抗原
See all PKLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-550
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原理
- KPYR Antibody
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特异性
- KPYR Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein at AA range: 510-550
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
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别名
- KPYR
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背景
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Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: PKLR PK1 PKL
Protein Name: Pyruvate kinase isozymes R/L (EC 2.7.1.40) (Pyruvate kinase 1) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase)
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基因ID
- 5313
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UniProt
- P30613
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途径
- Ribonucleoside Biosynthetic Process
抗原
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