PKM2 抗体 (AA 301-350)
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Quick Overview for PKM2 抗体 (AA 301-350) (ABIN8124183)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-350
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原理
- PKM2 Antibody
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特异性
- This antibody detects endogenous levels of human PKM2
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human PKM2 AA range: 301-350
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亚型
- IgG
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应用备注
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
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Synonyms: Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58)
Background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011],
Gene Name: PKM OIP3 PK2 PK3 PKM2
Protein Name: PKM2
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基因ID
- 5315
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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