PRKAB2 抗体
Our Local Distributor
北京 101111
Quick Overview for PRKAB2 抗体 (ABIN8124082)
抗原
See all PRKAB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- AMPKβ2 Antibody
-
特异性
- The antibody detects endogenous AMPKβ2 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Recombinant Protein of AMPKbeta2
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
-
别名
- AMPKbeta2
-
背景
-
Synonyms: PRKAB2, 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
Gene Name: PRKAB2
Protein Name: 5'-AMP-activated protein kinase subunit beta-2
-
基因ID
- 5565
-
UniProt
- O43741
-
途径
- AMPK Signaling, Warburg Effect
抗原
-