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PKN1 抗体

The 兔 多克隆 anti-PKN1 antibody (ABIN8124076) specifically detects PKN1 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8124076
发货至: 中国
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Quick Overview for PKN1 抗体 (ABIN8124076)

抗原

See all PKN1 抗体
PKN1 (Protein Kinase N1 (PKN1))

适用

  • 37
  • 11
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 11
兔

克隆类型

  • 25
  • 12
多克隆

标记

  • 23
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PKN1 antibody is un-conjugated

应用范围

  • 21
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    PKN Antibody

    特异性

    PKN Polyclonal Antibody detects endogenous levels of PKN protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human PKN.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PKN1 (Protein Kinase N1 (PKN1))

    别名

    PKN

    背景

    Synonyms: PKN1, PAK1, PKN, PRK1, PRKCL1, Serine/threonine-protein kinase N1, Protease-activated kinase 1, PAK-1, Protein kinase C-like 1, Protein kinase C-like PKN, Protein kinase PKN-alpha, Protein-kinase C-related kinase 1, Serine-threonine protein

    Background: protein kinase N1(PKN1) Homo sapiens The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

    Gene Name: PKN1

    Protein Name: Serine/threonine-protein kinase N1

    基因ID

    5585

    UniProt

    Q16512
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