PTRF 抗体 (AA 90-170)
Our Local Distributor
北京 101111
Quick Overview for PTRF 抗体 (AA 90-170) (ABIN8123876)
抗原
See all PTRF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 90-170
-
原理
- PTRF Antibody
-
特异性
- PTRF Polyclonal Antibody detects endogenous levels of protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human protein . at AA range: 90-170
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
-
别名
- PTRF
-
背景
-
Background: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrop
Gene Name: PTRF FKSG13
Protein Name: Polymerase I and transcript release factor (Cavin-1)
-
基因ID
- 284119
-
UniProt
- Q6NZI2
抗原
-