POLG 抗体
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北京 101111
Quick Overview for POLG 抗体 (ABIN8123859)
抗原
See all POLG 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DPOG1 Antibody
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特异性
- DPOG1 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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别名
- DPOG1
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背景
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Background: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit.The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: POLG MDP1 POLG1 POLGA
Protein Name: DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)
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基因ID
- 5428
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UniProt
- P54098
抗原
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