PMS2 抗体
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北京 101111
Quick Overview for PMS2 抗体 (ABIN8123823)
抗原
See all PMS2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PMS2 Rabbit mAb
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特异性
- This antibody detects endogenous levels of PMS2 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibody
PMS2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E9D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) antibodyPMS2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G12E1 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E4G11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6A12H9 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) antibodyKO Validated PMS2 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB3205 unconjugated Recombinant Antibody
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 390-670) antibodyPMS2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) antibodyPMS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 550-600) antibodyPMS2 适用: 人 WB, FACS, IP 宿主: 兔 Monoclonal BLR142H unconjugated Recombinant Antibody
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:500-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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别名
- PMS2
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背景
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Synonyms: Mismatch repair endonuclease PMS2 (EC 3. 1.-.-, DNA mismatch repair protein PMS2, PMS1 protein homolog 2)
Background: The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA (X) 2E (X) 4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC, also known as Lynch syndrome) and Turcot syndrome
Gene Name: PMS2 PMSL2
Protein Name: PMS2
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基因ID
- 5395
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UniProt
- P54278
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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