PPARA 抗体 (pSer21)
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Quick Overview for PPARA 抗体 (pSer21) (ABIN8123671)
抗原
See all PPARA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer21
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原理
- PPAR α (Phospho Ser21) Antibody
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特异性
- This antibody detects endogenous levels of Human PPAR α (Phospho Ser21)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human PPAR alpha (Phospho Ser21)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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别名
- PPAR alpha
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背景
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Synonyms: Peroxisome proliferator-activated receptor alpha (PPAR-alpha, Nuclear receptor subfamily 1 group C member 1)
Background: function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.,online information:Peroxisome proliferator-activated receptor entry,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.,tissue specificity:Skeletal muscle, liver, heart and kidney.,
Gene Name: PPARA NR1C1 PPAR
Protein Name: PPAR α (Phospho Ser21)
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基因ID
- 5465
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UniProt
- Q07869
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
抗原
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