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PPARA 抗体 (AA 1-468)

PPARA 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1331CT894-186-143 unconjugated
产品编号 ABIN1944858
发货至: 中国
  • 抗原 See all PPARA 抗体
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    抗原表位
    • 16
    • 16
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-468
    适用
    • 99
    • 90
    • 67
    • 18
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 102
    • 13
    小鼠
    克隆类型
    • 104
    • 11
    单克隆
    标记
    • 50
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This PPARA antibody is un-conjugated
    应用范围
    • 101
    • 45
    • 40
    • 39
    • 39
    • 16
    • 14
    • 12
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
    克隆位点
    1331CT894-186-143
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PPARA Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Cho, Lee, Choi, Yang, Tae Hong, Kim, Yoon: "Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha." in: Immunopharmacology and immunotoxicology, Vol. 31, Issue 3, pp. 459-67, (2009) (PubMed).

    Kobayashi, Kodani, Nozawa, Endo, Sawasaki: "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system." in: FEBS letters, Vol. 582, Issue 18, pp. 2737-44, (2008) (PubMed).

    Tugwood, Aldridge, Lambe, Macdonald, Woodyatt: "Peroxisome proliferator-activated receptors: structures and function." in: Annals of the New York Academy of Sciences, Vol. 804, pp. 252-65, (1997) (PubMed).

    Mukherjee, Jow, Noonan, McDonnell: "Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators." in: The Journal of steroid biochemistry and molecular biology, Vol. 51, Issue 3-4, pp. 157-66, (1995) (PubMed).

  • 抗原
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    别名
    PPARA (PPARA 产品)
    别名
    NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, LOC100136415 antibody, PPARALPHA antibody, nr1c1 antibody, xPPARalpha antibody, xppara antibody, 4933429D07Rik antibody, AW742785 antibody, Nr1c1 antibody, PPAR-alpha antibody, Ppar antibody, peroxisome proliferator activated receptor alpha antibody, peroxisome proliferator-activated receptor alpha antibody, peroxisome proliferator activated receptor alpha L homeolog antibody, PPARA antibody, LOC100136415 antibody, ppara.L antibody, Ppara antibody, ppara antibody
    背景
    Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
    分子量
    52225
    基因ID
    5465
    UniProt
    Q07869
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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