PGC 抗体
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北京 101111
Quick Overview for PGC 抗体 (ABIN8123631)
抗原
See all PGC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PEPC Antibody
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特异性
- The antibody detects endogenous PEPC protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic Peptide of PEPC
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亚型
- IgG
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应用备注
- WB 1:2000-5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PGC (Pepsinogen C (PGC))
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别名
- PEPC
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背景
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Synonyms: PGC, Gastricsin, Pepsinogen C
Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
Gene Name: PGC
Protein Name: Gastricsin
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UniProt
- P20142
抗原
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