PAX5 抗体 (AA 300-383)
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北京 101111
Quick Overview for PAX5 抗体 (AA 300-383) (ABIN8123566)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 300-383
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原理
- PAX-5 mouse mAb
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特异性
- This antibody detects endogenous levels of PAX-5 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 300 - 383 of the human PAX - 5 protein.
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亚型
- IgG
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anti-Paired Box 5 (PAX5) (AA 192-301) antibody
PAX5 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PAX5-3735 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7D3 unconjugated
anti-Paired Box 5 (PAX5) (AA 217-282) antibodyPAX5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 6I4 unconjugated
anti-Paired Box 5 (PAX5) (AA 217-282) antibodyPAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyVerified PAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Paired Box 5 (PAX5) (AA 178-207) antibodyPAX5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 178-207) antibodyPAX5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20217 unconjugated
anti-Paired Box 5 (PAX5) antibodyPAX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal rPAX5-2060 unconjugated Recombinant Antibody
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- PAX5 (Paired Box 5 (PAX5))
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别名
- PAX-5
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背景
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Synonyms: Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)
Background: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t (9,14) (p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: PAX5
Protein Name: PAX-5
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基因ID
- 5079
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UniProt
- Q02548
抗原
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