Osteocalcin 抗体
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北京 101111
Quick Overview for Osteocalcin 抗体 (ABIN8123531)
抗原
See all Osteocalcin (BGLAP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Osteocalcin Rabbit mAb
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特异性
- This antibody detects endogenous levels of Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein) protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:100-1:500 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Osteocalcin (BGLAP)
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别名
- Osteocalcin
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背景
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Synonyms: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1) , but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],
Gene Name: BGLAP
Protein Name: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
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基因ID
- 632
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UniProt
- P02818
抗原
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