NOTCH4 抗体 (Cleaved-Val1467)
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北京 101111
Quick Overview for NOTCH4 抗体 (Cleaved-Val1467) (ABIN8123380)
抗原
See all NOTCH4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Val1467
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原理
- NOTCH4 (Cleaved-Val1467) Antibody
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特异性
- This antibody detects endogenous levels of Human,Monkey NOTCH4 (Cleaved-Val1467, protein was cleaved amino acid sequence between 1466-1467 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human NOTCH4 (Cleaved-Val1467)
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NOTCH4 (Notch 4 (NOTCH4))
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别名
- NOTCH4
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背景
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Synonyms: Neurogenic locus notch homolog protein 4 (Notch 4, hNotch4) [Cleaved into: Notch 4 extracellular truncation, Notch 4 intracellular domain]
Background: notch 4(NOTCH4) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which
Gene Name: NOTCH4 INT3
Protein Name: NOTCH4 (Cleaved-Val1467)
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基因ID
- 4855
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UniProt
- Q99466
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途径
- Notch Signaling
抗原
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