NAIP 抗体 (AA 1191-1240)
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北京 101111
Quick Overview for NAIP 抗体 (AA 1191-1240) (ABIN8123355)
抗原
See all NAIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1191-1240
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原理
- NAIP Antibody
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特异性
- The antibody detects endogenous NAIP
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 1191-1240
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亚型
- IgG
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应用备注
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
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别名
- NAIP
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背景
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Synonyms: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)
Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1.The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref
Gene Name: NAIP BIRC1
Protein Name: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)
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基因ID
- 4671
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UniProt
- Q13075
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途径
- Apoptosis, Inflammasome
抗原
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