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CPEB1 抗体 (AA 451-550) (HRP)

This HRP-conjugated 兔 多克隆 anti-CPEB1 antibody specifically detects CPEB1 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN761510
发货至: 中国
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中国
北京 101111
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Quick Overview for CPEB1 抗体 (AA 451-550) (HRP) (ABIN761510)

抗原

See all CPEB1 抗体
CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

适用

  • 57
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宿主

  • 54
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克隆类型

  • 46
  • 11
多克隆

标记

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This CPEB1 antibody is conjugated to HRP

应用范围

  • 51
  • 21
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  • 4
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 9
    • 8
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    • 2
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    • 1
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    AA 451-550

    预测反应

    Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CPEB1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

    别名

    CPEB1

    背景

    Synonyms: CPE-binding protein 1, CPE-BP1, CPEB 1, CPEB, CPEB1, CPEB1 protein, CPEB1_HUMAN, Cytoplasmic polyadenylation binding protein 1, Cytoplasmic polyadenylation element binding protein, Cytoplasmic polyadenylation element binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1

    Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

    基因ID

    64506

    途径

    Synaptic Membrane
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