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NKX2-1 抗体 (AA 50-150)

The 兔 单克隆 anti-NKX2-1 antibody (Clone AB1688) (ABIN8123347) specifically detects NKX2-1 in IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8123347
发货至: 中国
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Quick Overview for NKX2-1 抗体 (AA 50-150) (ABIN8123347)

抗原

See all NKX2-1 抗体
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

适用

  • 111
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  • 1
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人, 小鼠

宿主

  • 63
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兔

克隆类型

  • 77
  • 34
单克隆

标记

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  • 1
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This NKX2-1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

AB1688
  • 抗原表位

    • 10
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    • 1
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    AA 50-150

    原理

    Thyroid transcription factor-1 (TTF1) Rabbit mAb (Ready to Use)

    特异性

    The antibody can specifically recognize human TTF1 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 50 - 150 of the human Thyroid transcription factor - 1 protein.

    亚型

    IgG
  • 应用备注

    It has been optimized for direct use, requiring no further dilution.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze

    储存条件

    4 °C

    储存方法

    Store at 4°C. Avoid freeze.
  • 抗原

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    别名

    Thyroid transcription factor-1

    背景

    Synonyms: AV026640,BCH,Benign chorea,BHC,Homeobox protein NK 2 homolog A,Homeobox protein NK-2 homolog A,Homeobox protein Nkx 2. 1,Homeobox protein Nkx-2. 1,Homeobox protein Nkx2. 1,NK 2,NK 2 homolog A,NK2,NK2 homeobox 1,NK2, drosophila, homolog of, A,NK2. 1, Mouse, homolog of,Nkx 2 1,NKX 2. 1,NKX 2A,NKX2 1,Nkx2-1,NKX2. 1,NKX21_HUMAN,NKX2A,T EBP,T/EBP,TEBP,Thyroid nuclear factor 1,Thyroid nuclear factor,Thyroid specific enhancer binding protein,Thyroid transcription factor 1,Tin man,Tinman,TITF 1,TITF1,TTF 1,TTF-1,TTF1

    Background: Thyroid transcription factor 1 (TTF- 1) is a nuclear protein with a molecular weight of 38- 40 kDa. It is the basic material for thyroid differentiation and the regulation of thyroglobulin secretion. It can promote the transport of thyroid peroxidase and iodine / sodium. TTF- 1 is mainly distributed in type II alveolar epithelium, respiratory epithelium and Clara cells of thyroid and lung in adult tissues, but it is not expressed in type I alveolar epithelium. It is mainly used for the diagnosis of small cell lung cancer, the differential diagnosis of primary lung adenocarcinoma from metastatic adenocarcinoma, and the differential diagnosis of lung cancer from malignant mesothelioma and paraganglioma of pleura.

    Gene Name: NKX2-1

    Protein Name: Thyroid transcription factor-1

    基因ID

    7080

    UniProt

    P43699

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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