NKX2-1 抗体 (AA 50-150)
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北京 101111
Quick Overview for NKX2-1 抗体 (AA 50-150) (ABIN8123347)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-150
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原理
- Thyroid transcription factor-1 (TTF1) Rabbit mAb (Ready to Use)
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特异性
- The antibody can specifically recognize human TTF1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 50 - 150 of the human Thyroid transcription factor - 1 protein.
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亚型
- IgG
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应用备注
- It has been optimized for direct use, requiring no further dilution.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Avoid freeze.
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- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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别名
- Thyroid transcription factor-1
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背景
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Synonyms: AV026640,BCH,Benign chorea,BHC,Homeobox protein NK 2 homolog A,Homeobox protein NK-2 homolog A,Homeobox protein Nkx 2. 1,Homeobox protein Nkx-2. 1,Homeobox protein Nkx2. 1,NK 2,NK 2 homolog A,NK2,NK2 homeobox 1,NK2, drosophila, homolog of, A,NK2. 1, Mouse, homolog of,Nkx 2 1,NKX 2. 1,NKX 2A,NKX2 1,Nkx2-1,NKX2. 1,NKX21_HUMAN,NKX2A,T EBP,T/EBP,TEBP,Thyroid nuclear factor 1,Thyroid nuclear factor,Thyroid specific enhancer binding protein,Thyroid transcription factor 1,Tin man,Tinman,TITF 1,TITF1,TTF 1,TTF-1,TTF1
Background: Thyroid transcription factor 1 (TTF- 1) is a nuclear protein with a molecular weight of 38- 40 kDa. It is the basic material for thyroid differentiation and the regulation of thyroglobulin secretion. It can promote the transport of thyroid peroxidase and iodine / sodium. TTF- 1 is mainly distributed in type II alveolar epithelium, respiratory epithelium and Clara cells of thyroid and lung in adult tissues, but it is not expressed in type I alveolar epithelium. It is mainly used for the diagnosis of small cell lung cancer, the differential diagnosis of primary lung adenocarcinoma from metastatic adenocarcinoma, and the differential diagnosis of lung cancer from malignant mesothelioma and paraganglioma of pleura.
Gene Name: NKX2-1
Protein Name: Thyroid transcription factor-1
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基因ID
- 7080
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UniProt
- P43699
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
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