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MYLK 抗体 (pTyr464)

The 兔 多克隆 anti-MYLK antibody (ABIN8123149) specifically detects MYLK in ELISA, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8123149
发货至: 中国
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Quick Overview for MYLK 抗体 (pTyr464) (ABIN8123149)

抗原

See all MYLK 抗体
MYLK (Myosin Light Chain Kinase (MYLK))

适用

  • 102
  • 53
  • 43
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 94
  • 5
  • 3
  • 1
兔

克隆类型

  • 79
  • 24
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MYLK antibody is un-conjugated

应用范围

  • 63
  • 49
  • 41
  • 24
  • 22
  • 14
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  • 13
  • 7
  • 5
  • 3
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  • 1
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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 12
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    • 2
    • 2
    • 2
    • 2
    • 1
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    pTyr464

    原理

    MYLK (phospho Tyr464) Antibody

    特异性

    Phospho-MYLK (Y464) Polyclonal Antibody detects endogenous levels of MYLK protein only when phosphorylated at Y464.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized phospho-peptide around the phosphorylation site of human MYLK (phospho Tyr464)

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MYLK (Myosin Light Chain Kinase (MYLK))

    别名

    MYLK

    背景

    Synonyms: MYLK; MLCK; MLCK1; MYLK1; Myosin light chain kinase; smooth muscle; MLCK; smMLCK; Kinase-related protein; KRP; Telokin

    Background: myosin light chain kinase(MYLK) Homo sapiens This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity.This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been

    Gene Name: MYLK

    Protein Name: Myosin light chain kinase smooth muscle

    基因ID

    4638

    UniProt

    Q15746
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