MLH1 抗体
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北京 101111
Quick Overview for MLH1 抗体 (ABIN8123090)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MLH1 mouse mAb
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特异性
- This antibody detects endogenous levels of MLH1 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- Recombinant protein of the human MLH1 protein.
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亚型
- IgG
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应用备注
- IHC, 1:100-1:400 | WB, 1:2000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
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Synonyms: DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1
Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009],
Gene Name: MLH1 COCA2
Protein Name: MutL Protein Homolog 1
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基因ID
- 4292
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UniProt
- P40692
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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