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MLH1 抗体 (AA 400-500)

The 小鼠 单克隆 anti-MLH1 antibody (Clone AB1558) (ABIN8123089) specifically detects MLH1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN8123089
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MLH1 抗体 (AA 400-500) (ABIN8123089)

抗原

See all MLH1 抗体
MLH1 (MutL Homolog 1 (MLH1))

适用

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人

宿主

  • 128
  • 63
小鼠

克隆类型

  • 104
  • 87
单克隆

标记

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This MLH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

AB1558
  • 抗原表位

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    AA 400-500

    原理

    MutL Protein Homolog 1 (MLH1) mouse mAb

    特异性

    This antibody detects endogenous levels of MLH1 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 400 - 500 of the human MutL Protein Homolog 1 protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    MLH1 (MutL Homolog 1 (MLH1))

    别名

    MutL Protein Homolog 1

    背景

    Synonyms: DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1

    Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009],

    Gene Name: MLH1 COCA2

    Protein Name: MutL Protein Homolog 1

    基因ID

    4292

    UniProt

    P40692

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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