MBTPS1 抗体 (AA 180-260)
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北京 101111
Quick Overview for MBTPS1 抗体 (AA 180-260) (ABIN8122861)
抗原
See all MBTPS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-260
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原理
- SKI-1 Antibody
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特异性
- SKI-1 Polyclonal Antibody detects endogenous levels of SKI-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from SKI-1 . at AA range: 180-260
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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别名
- SKI-1
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背景
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Synonyms: MBTPS1, KIAA0091, S1P, SKI1, Membrane-bound transcription factor site-1 protease, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, SKI-1
Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014],
Gene Name: MBTPS1
Protein Name: Membrane-bound transcription factor site-1 protease
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基因ID
- 8720
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UniProt
- Q14703
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途径
- ER-Nucleus Signaling
抗原
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