MMP7 抗体 (Cleaved-Tyr95)
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北京 101111
Quick Overview for MMP7 抗体 (Cleaved-Tyr95) (ABIN8122803)
抗原
See all MMP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Tyr95
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原理
- MMP7 (Cleaved-Tyr95) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat MMP7 (Cleaved-Tyr95, protein was cleaved amino acid sequence between 94-95 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human MMP7 (Cleaved-Tyr95)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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别名
- MMP7
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背景
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Synonyms: Matrilysin (EC 3.4.24.23, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase)
Background: catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,
Gene Name: MMP7 MPSL1 PUMP1
Protein Name: MMP7 (Cleaved-Tyr95)
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基因ID
- 4316
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UniProt
- P09237
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途径
- Production of Molecular Mediator of Immune Response
抗原
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