LRP5 抗体 (AA 1047-1097)
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北京 101111
Quick Overview for LRP5 抗体 (AA 1047-1097) (ABIN8122678)
抗原
See all LRP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1047-1097
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原理
- LRP5 Antibody
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特异性
- This antibody detects endogenous levels of LRP5 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human LRP5 AA range: 1047-1097
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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别名
- LRP5
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背景
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Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
Gene Name: LRP5 LR3 LRP7
Protein Name: LRP5
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基因ID
- 4041
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UniProt
- O75197
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途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
抗原
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