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KISS1 抗体

The 兔 多克隆 anti-KISS1 antibody (ABIN8122567) specifically detects KISS1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8122567
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KISS1 抗体 (ABIN8122567)

抗原

See all KISS1 抗体
KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

适用

  • 37
  • 17
  • 3
人, 小鼠

宿主

  • 36
  • 5
兔

克隆类型

  • 36
  • 5
多克隆

标记

  • 30
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KISS1 antibody is un-conjugated

应用范围

  • 22
  • 13
  • 13
  • 5
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    KISS1 Antibody

    特异性

    KISS1 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

    别名

    KISS1

    背景

    Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by R

    Gene Name: KISS1 PP5098

    Protein Name: Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54)Kisspeptin-14Kisspeptin-13Kisspeptin-10]

    基因ID

    3814

    UniProt

    Q15726

    途径

    Positive Regulation of Peptide Hormone Secretion
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