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KISS1 抗体 (AA 115-145)

KISS1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB53799 unconjugated
产品编号 ABIN6243763
发货至: 中国
  • 抗原 See all KISS1 抗体
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    抗原表位
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-145
    适用
    • 32
    • 16
    • 4
    宿主
    • 32
    • 4
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KISS1 antibody is un-conjugated
    应用范围
    • 19
    • 14
    • 10
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KISS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the human region of human KISS1.
    克隆位点
    RB53799
    亚型
    Ig Fraction
    Top Product
    Discover our top product KISS1 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:2000. WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    别名
    KISS1 (KISS1 产品)
    别名
    HH13 antibody, KiSS-1 antibody, metastatin antibody, Eseptin antibody, KiSS-1 metastasis-suppressor antibody, KISS1 antibody, kiss1 antibody, Kiss1 antibody
    背景
    Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
    分子量
    14705
    UniProt
    Q15726
    途径
    Positive Regulation of Peptide Hormone Secretion
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