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JAK3 抗体

The 兔 单克隆 anti-JAK3 antibody is suitable to detect JAK3 in samples from 人. It has been validated for WB, ELISA, IF 和 IP.
产品编号 ABIN8122386
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for JAK3 抗体 (ABIN8122386)

抗原

See all JAK3 抗体
JAK3 (Janus Kinase 3 (JAK3))

适用

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人

宿主

  • 100
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兔

克隆类型

  • 80
  • 25
单克隆

标记

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This JAK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB1912
  • 原理

    JAK3 Rabbit mAb

    特异性

    This antibody detects endogenous levels of JAK3 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    JAK3 (Janus Kinase 3 (JAK3))

    别名

    JAK3

    背景

    Synonyms: JAK3, Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Leukocyte janus kinase, L-JAK

    Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008],

    Gene Name: JAK3

    Protein Name: JAK3

    基因ID

    3718

    UniProt

    P52333

    途径

    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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