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JAK1 抗体

The 兔 单克隆 anti-JAK1 antibody (Clone AB2121) (ABIN8122378) specifically detects JAK1 in WB, IHC, ELISA, IF 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8122378
发货至: 中国
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Quick Overview for JAK1 抗体 (ABIN8122378)

抗原

See all JAK1 抗体
JAK1 (Janus Kinase 1 (JAK1))

适用

  • 135
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人, 小鼠, 大鼠

宿主

  • 113
  • 26
  • 1
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兔

克隆类型

  • 91
  • 50
单克隆

标记

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This JAK1 antibody is un-conjugated

应用范围

  • 99
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB2121
  • 原理

    JAK1 Rabbit mAb

    特异性

    This antibody detects endogenous levels of JAK1 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:100-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    JAK1 (Janus Kinase 1 (JAK1))

    别名

    JAK1

    背景

    Synonyms: Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1,

    Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

    Gene Name: JAK1 JAK1A JAK1B

    Protein Name: JAK1

    基因ID

    3716

    UniProt

    P23458

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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