JAK1 抗体 (pTyr1034)
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北京 101111
Quick Overview for JAK1 抗体 (pTyr1034) (ABIN8122377)
抗原
See all JAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1034
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原理
- Jak1(Phospho Tyr1034/1035) Antibody
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特异性
- This antibody detects endogenous levels of Human Mouse Rat Jak1(phospho-Tyr1034 or 1035)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human Jak1(Tyr1034 and 1035)
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亚型
- IgG
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应用备注
- WB 1:200-1000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JAK1 (Janus Kinase 1 (JAK1))
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别名
- Jak1
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背景
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Synonyms: Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: JAK1 JAK1A JAK1B
Protein Name: Jak1(Tyr1034/1035)
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基因ID
- 3716
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UniProt
- P23458
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
抗原
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