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IRF1 抗体

This 兔 单克隆 antibody specifically detects IRF1 in WB, IHC, ELISA, IF 和 IP. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8122286
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRF1 抗体 (ABIN8122286)

抗原

See all IRF1 抗体
IRF1 (Interferon Regulatory Factor 1 (IRF1))

适用

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人, 小鼠, 大鼠

宿主

  • 108
  • 5
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兔

克隆类型

  • 88
  • 26
单克隆

标记

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This IRF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB2271
  • 原理

    IRF-1 Rabbit mAb

    特异性

    This antibody detects endogenous levels of Interferon regulatory factor 1 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IHC, 1:100-1:400 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    IRF1 (Interferon Regulatory Factor 1 (IRF1))

    别名

    IRF-1

    背景

    Synonyms: IRF1,Interferon regulatory factor 1,IRF-1

    Background: The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017]

    Gene Name: IRF1

    Protein Name: Interferon regulatory factor 1

    基因ID

    3659

    UniProt

    P10914

    途径

    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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