电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Importin 9 抗体

The 兔 多克隆 anti-Importin 9 antibody is suitable to detect Importin 9 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8122170
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Importin 9 抗体 (ABIN8122170)

抗原

See all Importin 9 (IPO9) 抗体
Importin 9 (IPO9)

适用

  • 119
  • 49
  • 31
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 110
  • 9
  • 1
兔

克隆类型

  • 82
  • 38
多克隆

标记

  • 54
  • 7
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Importin 9 antibody is un-conjugated

应用范围

  • 92
  • 45
  • 36
  • 27
  • 13
  • 13
  • 12
  • 9
  • 9
  • 6
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    IPO9 Antibody

    特异性

    IPO9 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Importin 9 (IPO9)

    别名

    IPO9

    背景

    Background: function:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.,similarity:Belongs to the importin beta family.,similarity:Contains 1 importin N-terminal domain.,subunit:Binds with high affinity to RPS7 and RPL18A. The binding is coupled to RanGTP cycles. May bind H2A, H3, H4 histones (By similarity), RPL4 and RPL6 with low affinity. Interacts with PPP2R1A and PPP2R1B.,

    Gene Name: IPO9 IMP9 KIAA1192 RANBP9 HSPC273

    Protein Name: Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9)

    基因ID

    55705

    UniProt

    Q96P70

    途径

    Protein targeting to Nucleus
You are here: