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HDAC1 抗体 (acLys432)

Name: HDAC1 抗体 (acLys432)
SKU: ABIN8121983
Availability: OutOfStock

This 兔多克隆 antibody specifically detects HDAC1 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠和大鼠.

产品编号 ABIN8121983

发货至: 中国

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中国
北京 101111

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Quick Overview for HDAC1 抗体 (acLys432) (ABIN8121983)

抗原

See all HDAC1 抗体

HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This HDAC1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product HDAC1 Primary Antibody

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acLys432

原理

HDAC1 (Acetyl Lys432) Antibody

特异性

This antibody detects endogenous levels of Human,Mouse,Rat HDAC1 (Acetyl Lys432)

纯化方法

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

免疫原

Synthesized peptide derived from human HDAC1 (Acetyl Lys432)

亚型

IgG
anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IF, ICC, IP, IHC (p), ChIP, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 5C11 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal E22 unconjugated

anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 IHC, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 450-482) antibody
HDAC1 适用: 人 WB, IHC, ELISA, IF, FM, MA 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibody
Verified HDAC1 适用: 人, 小鼠 WB, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 449-482), (C-Term) antibody
HDAC1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB5642 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibody
HDAC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 斑马鱼, 豚鼠, 马, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000-2000 ELISA 1:5000-20000

限制

仅限研究用
状态

Liquid

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C/1 year

有效期

12 months
抗原

HDAC1 (Histone Deacetylase 1 (HDAC1))

别名

HDAC1

背景

Synonyms: Histone deacetylase 1 (HD1, EC 3.5.1.98)
Background: catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.,PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes.,PTM:Sumoylated on Lys-444 and Lys-476, which promotes enzymatic activity. Desumoylated by SENP1.,similarity:Belongs to the histone deacetylase family. Type 1 subfamily.,subunit:Part of the core histone deacetylase (HDAC) complex composed of HDAC1, HDAC2, RBBP4 and RBBP7. The core complex associates with MTA2, MBD2, MBD3, MTA1L1, CHD3 and CHD4 to form the nucleosome remodeling and histone deacetylation (NuRD) complex, or with SIN3, SAP18 and SAP30 to form the SIN3 HDAC complex. Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Associates with the 9-1-1 complex, interacts with HUS1. Found in a complex with DNMT3A and HDAC7. Interacts with BCOR, BRMS1L, DAXX, DNMT1, EP300, HCFC1, NFE4, PCAF, PHB2, MIER1, KDM4A, MINT, NRIP1, PRDM6, RERE, SETDB1, SUV39H1, TGIF, TGIF2, UHRF1, UHRF2 and ZNF541. Interacts with the non-histone region of H2AFY. Interacts with HDAC9. Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2. Interacts with BANP, CBFA2T3 and KDM5B. Interacts with SAP30L. Interacts with E4F1. Interacts with KFL1 (By similarity). Interacts with SV40 large T antigen.,tissue specificity:Ubiquitous, with higher levels in heart, pancreas and testis, and lower levels in kidney and brain.,
Gene Name: HDAC1 RPD3L1
Protein Name: HDAC1 (Acetyl Lys432)

基因ID

3065

UniProt

Q13547

途径

Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis