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HDAC1 抗体 (AA 300-482)

The 小鼠 单克隆 anti-HDAC1 antibody is suitable to detect HDAC1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN8121981
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC1 抗体 (AA 300-482) (ABIN8121981)

抗原

See all HDAC1 抗体
HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This HDAC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

AB2383
  • 抗原表位

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    AA 300-482

    原理

    HDAC1 mouse mAb

    特异性

    This antibody detects endogenous levels of HDAC1 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 300 - 482 of the human HDAC1 protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    HDAC1 (Histone Deacetylase 1 (HDAC1))

    别名

    HDAC1

    背景

    Synonyms: Histone deacetylase 1 (HD1) (EC 3. 5. 1. 98)

    Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],

    Gene Name: HDAC1 RPD3L1

    Protein Name: HDAC1

    基因ID

    3065

    UniProt

    Q13547

    途径

    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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