Hexokinase 2 抗体
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北京 101111
Quick Overview for Hexokinase 2 抗体 (ABIN8121949)
抗原
See all Hexokinase 2 (HK2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Hexokinase II Rabbit mAb
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特异性
- This antibody detects endogenous levels of Hexokinase II protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:400 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Hexokinase 2 (HK2)
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别名
- Hexokinase II
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背景
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Synonyms: HK2, Hexokinase-2, Hexokinase type II, HK II, Muscle form hexokinase
Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009],
Gene Name: HK2
Protein Name: Hexokinase II
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基因ID
- 3099
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UniProt
- P52789
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
抗原
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