Glutaredoxin 1 抗体 (AA 8-58)
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Quick Overview for Glutaredoxin 1 抗体 (AA 8-58) (ABIN8121705)
抗原
See all Glutaredoxin 1 (GRX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-58
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原理
- Glutaredoxin-1 Antibody
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特异性
- This antibody detects endogenous levels of human Glutaredoxin-1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Glutaredoxin 1 (GRX1)
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别名
- Glutaredoxin-1
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背景
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Synonyms: Glutaredoxin-1 (Thioltransferase-1; TTase-1)
Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],
Gene Name: GLRX GRX
Protein Name: Glutaredoxin-1
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基因ID
- 2745
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UniProt
- P35754
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途径
- Cell RedoxHomeostasis
抗原
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