Glutaredoxin 1 抗体 (AA 40-120)
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Quick Overview for Glutaredoxin 1 抗体 (AA 40-120) (ABIN7228674)
抗原
See all Glutaredoxin 1 (GRX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- Rabbit Anti-GLRX1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GLRX1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human GLRX1 protein at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Glutaredoxin 1 (GRX1)
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别名
- GLRX1
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背景
- Glutaredoxin-1, Thioltransferase-1, TTase-1GLRX encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
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分子量
- 11kD
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基因ID
- 2745
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UniProt
- P35754
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途径
- Cell RedoxHomeostasis
抗原
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