GCK 抗体 (AA 221-270)
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Quick Overview for GCK 抗体 (AA 221-270) (ABIN8121675)
抗原
See all GCK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-270
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原理
- GCK/GLK Antibody
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特异性
- GCK/GLK Polyclonal Antibody detects endogenous levels of GCK/GLK
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human GCK/GLK. at AA range: 221-270
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亚型
- IgG
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应用备注
- WB 1:500-2000, ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GCK (Glucokinase (Hexokinase 4) (GCK))
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别名
- GCK/GLK
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背景
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Synonyms: Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein) Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)
Background: mitogen-activated protein kinase kinase kinase kinase 2(MAP4K2) Homo sapiens The protein encoded byThis gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Gene Name: MAP4K2/MAP4K3
Protein Name: GCK/GLK
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基因ID
- 5871
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UniProt
- Q12851
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途径
- MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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