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GCK 抗体 (AA 221-270)

The 兔 多克隆 anti-GCK antibody is suitable to detect GCK in samples from 人 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8121675
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GCK 抗体 (AA 221-270) (ABIN8121675)

抗原

See all GCK 抗体
GCK (Glucokinase (Hexokinase 4) (GCK))

适用

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人, 大鼠

宿主

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兔

克隆类型

  • 68
  • 7
多克隆

标记

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This GCK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 221-270

    原理

    GCK/GLK Antibody

    特异性

    GCK/GLK Polyclonal Antibody detects endogenous levels of GCK/GLK

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human GCK/GLK. at AA range: 221-270

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, ELISA 1:10000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GCK (Glucokinase (Hexokinase 4) (GCK))

    别名

    GCK/GLK

    背景

    Synonyms: Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein) Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)

    Background: mitogen-activated protein kinase kinase kinase kinase 2(MAP4K2) Homo sapiens The protein encoded byThis gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

    Gene Name: MAP4K2/MAP4K3

    Protein Name: GCK/GLK

    基因ID

    5871

    UniProt

    Q12851

    途径

    MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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