FGD4 抗体 (AA 291-341)
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Quick Overview for FGD4 抗体 (AA 291-341) (ABIN8121549)
抗原
See all FGD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 291-341
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原理
- FGD4 Antibody
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特异性
- This antibody detects endogenous levels of FGD4 at Human/Mouse/Rat
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human FGD4 AA range: 291-341
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亚型
- IgG
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anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) antibody
FGD4 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) (AA 157-186), (N-Term) antibodyFGD4 适用: 人 WB 宿主: 兔 Polyclonal RB32509 unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) (AA 99-198) antibodyFGD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) antibodyFGD4 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
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别名
- FGD4
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背景
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Synonyms: FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)
Background: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],
Gene Name: FGD4 FRABP ZFYVE6
Protein Name: FGD4
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基因ID
- 121512
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UniProt
- Q96M96
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途径
- Neurotrophin Signaling Pathway
抗原
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