FURIN 抗体 (AA 340-420)
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北京 101111
Quick Overview for FURIN 抗体 (AA 340-420) (ABIN8121543)
抗原
See all FURIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-420
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原理
- FURIN Antibody
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特异性
- FURIN Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 340-420
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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别名
- FURIN
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背景
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Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix m
Gene Name: FURIN FUR PACE PCSK3
Protein Name: Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)
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基因ID
- 5045
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UniProt
- P09958
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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