FAM111A 抗体
Our Local Distributor
北京 101111
Quick Overview for FAM111A 抗体 (ABIN8121366)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- FAM111A Rabbit mAb
-
特异性
- This antibody detects endogenous levels of FAM111A protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 |
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))
-
别名
- FAM111A
-
背景
-
Synonyms: FAM111A, KIAA1895, Serine protease FAM111A,
Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA) . Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia) , both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Gene Name: FAM111A, KIAA1895
Protein Name: FAM111A
-
基因ID
- 63901
-
UniProt
- Q96PZ2
抗原
-