FAM111A 抗体 (AA 264-314)
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北京 101111
Quick Overview for FAM111A 抗体 (AA 264-314) (ABIN8121365)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 264-314
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原理
- F111A Antibody
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特异性
- This antibody detects endogenous levels of F111A at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human F111A AA range: 264-314
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亚型
- IgG
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anti-Family with Sequence Similarity 111, Member A (FAM111A) (AA 26-179) antibody
FAM111A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 111, Member A (FAM111A) (AA 1-611) antibodyFAM111A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))
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别名
- F111A
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背景
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Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Gene Name: FAM111A KIAA1895
Protein Name: F111A
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基因ID
- 63901
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UniProt
- Q96PZ2
抗原
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