FBXW5 抗体 (AA 319-369)
Our Local Distributor
北京 101111
Quick Overview for FBXW5 抗体 (AA 319-369) (ABIN8121353)
抗原
See all FBXW5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 319-369
-
原理
- FBXW5 Antibody
-
特异性
- This antibody detects endogenous levels of FBXW5 at Human/Mouse/Rat
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human FBXW5 AA range: 319-369
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
-
别名
- FBXW5
-
背景
-
Synonyms: F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008],
Gene Name: FBXW5 FBW5 PP3971
Protein Name: FBXW5
-
基因ID
- 54461
-
UniProt
- Q969U6
抗原
-