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EIF2A 抗体 (pSer51)

This 小鼠 单克隆 antibody specifically detects EIF2A in WB, IF 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8121299
发货至: 中国
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Quick Overview for EIF2A 抗体 (pSer51) (ABIN8121299)

抗原

See all EIF2A 抗体
EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

适用

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人, 大鼠, 小鼠

宿主

  • 117
  • 19
  • 2
小鼠

克隆类型

  • 84
  • 54
单克隆

标记

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This EIF2A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA

克隆位点

AB2377
  • 抗原表位

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    • 1
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    • 1
    • 1
    pSer51

    原理

    eIF2α (Phospho Ser51) mouse mAb

    特异性

    This antibody detects endogenous levels of eIF2α (Phospho Ser51) protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthesized phosphopeptide corresponding to residues surrounding Ser51 of human eIF2alpha.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

    别名

    eIF2alpha

    背景

    Synonyms: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2-alpha) , EIF2S1, EIF2A

    Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1) , the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908) , and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al. , 1987 [PubMed 2948954]) . [supplied by OMIM, Feb 2010],

    Gene Name: EIF2S1

    Protein Name: eIF2α

    基因ID

    1965

    UniProt

    P05198

    途径

    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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