RAD18 抗体 (pSer403)
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北京 101111
Quick Overview for RAD18 抗体 (pSer403) (ABIN8121119)
抗原
See all RAD18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer403
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原理
- Rad18 (Phospho Ser403) Antibody
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特异性
- This antibody detects endogenous levels of Human Rad18 (phospho-Ser403)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human Rad18 (Ser403)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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别名
- Rad18
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背景
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Synonyms: E3 ubiquitin-protein ligase RAD18 (EC 6.3.2.-) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73)
Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008],
Gene Name: RAD18 RNF73
Protein Name: Rad18 (Ser403)
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基因ID
- 56852
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UniProt
- Q9NS91
抗原
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