NEDD4-2 抗体 (pSer448)
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Quick Overview for NEDD4-2 抗体 (pSer448) (ABIN8121118)
抗原
See all NEDD4-2 (NEDD4L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer448
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原理
- NEDD4L (Phospho Ser448) Antibody
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特异性
- This antibody detects endogenous levels of Human NEDD4L (phospho-Ser448)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human NEDD4L (Ser448)
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亚型
- IgG
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anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 836-955) antibody
NEDD4L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) antibodyNEDD4L 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyNEDD4L 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyKD Validated NEDD4L 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2910 unconjugated Recombinant Antibody
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyNEDD4L 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 275-325) antibodyNEDD4L 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (pSer448) antibodyNEDD4L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (pSer448) antibodyNEDD4L 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 289-494) antibodyNEDD4L 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 275-325) antibodyNEDD4L 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig WB, IHC, IP, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
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别名
- NEDD4L
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背景
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Synonyms: E3 ubiquitin-protein ligase NEDD4-like (EC 6.3.2.-) (NEDD4.2) (Nedd4-2)
Background: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
Gene Name: NEDD4L KIAA0439 NEDL3
Protein Name: NEDD4L (Ser448)
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基因ID
- 23327
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UniProt
- Q96PU5
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途径
- Negative Regulation of Transporter Activity
抗原
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