Dystrophin 抗体
Our Local Distributor
北京 101111
Quick Overview for Dystrophin 抗体 (ABIN8121097)
抗原
See all Dystrophin (DMD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Dystrophin Rabbit mAb
-
特异性
- This antibody detects endogenous levels of Dystrophin protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:500-1:2000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- Dystrophin (DMD)
-
别名
- Dystrophin
-
背景
-
Synonyms: Dystrophin
Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC) , which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD) , Becker muscular dystrophy (BMD) , or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Gene Name: DMD
Protein Name: Dystrophin
-
基因ID
- 1756
-
UniProt
- P11532
-
途径
- Skeletal Muscle Fiber Development
抗原
-