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Dystrophin 抗体

The 兔 多克隆 anti-Dystrophin antibody is suitable to detect Dystrophin in samples from 人, 小鼠 和 大鼠. It has been validated for IHC 和 IF.
产品编号 ABIN8121096
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Dystrophin 抗体 (ABIN8121096)

抗原

See all Dystrophin (DMD) 抗体
Dystrophin (DMD)

适用

  • 125
  • 30
  • 29
  • 3
  • 2
人, 小鼠, 大鼠

宿主

  • 75
  • 51
兔

克隆类型

  • 90
  • 36
多克隆

标记

  • 71
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dystrophin antibody is un-conjugated

应用范围

  • 67
  • 41
  • 32
  • 28
  • 26
  • 14
  • 10
  • 10
  • 10
  • 8
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    DMD Antibody

    特异性

    DMD Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    IHC 1:50-300. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Dystrophin (DMD)

    别名

    DMD

    背景

    Background: dystrophin(DMD) Homo sapiens The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as enc

    Gene Name: DMD

    Protein Name: Dystrophin

    基因ID

    1756

    UniProt

    P11532

    途径

    Skeletal Muscle Fiber Development
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