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DCLK1 抗体 (AA 514-564)

The 兔 多克隆 anti-DCLK1 antibody (ABIN8121064) specifically detects DCLK1 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8121064
发货至: 中国
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Quick Overview for DCLK1 抗体 (AA 514-564) (ABIN8121064)

抗原

See all DCLK1 抗体
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

适用

  • 115
  • 75
  • 48
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 106
  • 10
兔

克隆类型

  • 75
  • 41
多克隆

标记

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  • 9
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DCLK1 antibody is un-conjugated

应用范围

  • 85
  • 41
  • 29
  • 24
  • 23
  • 17
  • 13
  • 13
  • 6
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 514-564

    原理

    DCLK1 Antibody

    特异性

    This antibody detects endogenous levels of DCLK1 at Human/Mouse/Rat

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human DCLK1 AA range: 514-564

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    DCLK1

    背景

    Background: This gene encodes a member of the protein kinase superfamily and the doublecortin family.The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010],

    Gene Name: DCLK1 DCAMKL1 DCDC3A KIAA0369

    Protein Name: DCLK1

    基因ID

    9201

    UniProt

    O15075
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