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DCLK1 抗体 (N-Term)

DCLK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3059 unconjugated
产品编号 ABIN391323
发货至: 中国
  • 抗原 See all DCLK1 抗体
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    抗原表位
    • 15
    • 15
    • 9
    • 9
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 85
    • 45
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 84
    • 6
    • 1
    克隆类型
    • 76
    • 15
    多克隆
    标记
    • 34
    • 9
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCLK1 antibody is un-conjugated
    应用范围
    • 72
    • 43
    • 20
    • 17
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This DCAMKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCAMKL1.
    克隆位点
    RB3059
    亚型
    Ig Fraction
    Top Product
    Discover our top product DCLK1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Sala, Matthews, Speer, Torashima, Barthel, Grikscheit: "A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse." in: Tissue engineering. Part A, Vol. 17, Issue 13-14, pp. 1841-50, (2011) (PubMed).

    Tu, Quante, Bhagat, Takaishi, Cui, Yang, Muthuplani, Shibata, Fox, Pritchard, Wang: "IFN-? inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis." in: Cancer research, Vol. 71, Issue 12, pp. 4247-59, (2011) (PubMed).

    Shibata, Takaishi, Muthupalani, Pritchard, Whary, Rogers, Fox, Betz, Kaestner, Karin, Wang: "Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia." in: Gastroenterology, Vol. 138, Issue 3, pp. 1022-34.e1-10, (2010) (PubMed).

    Jin, Ramanathan, Quante, Baik, Yang, Wang, Tu, Gordon, Pritchard, Varro, Shulkes, Wang: "Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice." in: The Journal of clinical investigation, Vol. 119, Issue 9, pp. 2691-701, (2009) (PubMed).

    Gyamfi, Tanaka, He, Klaassen, Wan: "Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice." in: Toxicology and applied pharmacology, Vol. 234, Issue 2, pp. 166-78, (2009) (PubMed).

  • 抗原
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    别名
    DCAMKL1 (DCLK1 产品)
    别名
    DCLK1 antibody, DCAMKL1 antibody, dcamkl1 antibody, dclk1 antibody, wu:fc51f11 antibody, zgc:153709 antibody, MGC145348 antibody, CL1 antibody, CLICK1 antibody, DCDC3A antibody, DCLK antibody, 1700113D08Rik antibody, 2810480F11Rik antibody, AI836758 antibody, Click-I antibody, Cpg16 antibody, Dcamkl1 antibody, Dcl antibody, Dclk antibody, mKIAA0369 antibody, Ania4 antibody, doublecortin like kinase 1 antibody, doublecortin-like kinase 1a antibody, serine/threonine-protein kinase DCLK1 antibody, doublecortin-like kinase 2 antibody, doublecortin-like kinase 1 antibody, DCLK1 antibody, dclk1a antibody, LOC587664 antibody, dclk2 antibody, LOC100539645 antibody, Dclk1 antibody
    背景
    Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.
    分子量
    82224
    基因ID
    9201
    NCBI登录号
    NP_001182344, NP_001182345, NP_004725
    UniProt
    O15075
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