DNAJC2 抗体 (pSer47)
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Quick Overview for DNAJC2 抗体 (pSer47) (ABIN8121046)
抗原
See all DNAJC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer47
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原理
- DNAJC2/MPP11 (Phospho Ser47) Antibody
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特异性
- This antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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别名
- DNAJC2/MPP11
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背景
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Synonyms: DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Gene Name: DNAJC2 MPHOSPH11 MPP11 ZRF1
Protein Name: DNAJC2/MPP11 (Ser47)
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基因ID
- 27000
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UniProt
- Q99543
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途径
- Chromatin Binding
抗原
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