DNAJC2 抗体 (AA 1-140)
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- 抗原 See all DNAJC2 抗体
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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抗原表位
- AA 1-140
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNAJC2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)
- 亚型
- IgG
- Top Product
- Discover our top product DNAJC2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
- 别名
- DNAJC2 (DNAJC2 产品)
- 别名
- zrf1 antibody, ZRF1 antibody, MPHOSPH11 antibody, MPP11 antibody, ZUO1 antibody, AU020218 antibody, MIDA1 antibody, Zrf1 antibody, Zrf2 antibody, zgc:85671 antibody, DnaJ heat shock protein family (Hsp40) member C2 antibody, DnaJ (Hsp40) homolog, subfamily C, member 2 antibody, dnajc2 antibody, DNAJC2 antibody, Dnajc2 antibody
- 背景
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Background: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at \\\'Lys-119\\\' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5\\\'-GTCAAGC-3\\\'.
Aliases: AU020218 antibody, DnaJ (Hsp40) homolog subfamily C member 2 antibody, DnaJ homolog subfamily C member 2 antibody, Dnajc2 antibody, DNJC2_HUMAN antibody, M phase phosphoprotein 11 antibody, M-phase phosphoprotein 11 antibody, MGC105894 antibody, MIDA1 antibody, MPHOSPH11 antibody, MPP11 antibody, OTTMUSP00000031226 antibody, ZRF1 antibody, Zrf2 antibody, ZUO1 antibody, Zuotin related factor 1 antibody, Zuotin related factor 2 antibody, Zuotin-related factor 1 antibody
- UniProt
- Q99543
- 途径
- Chromatin Binding
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