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DNAJC2 抗体 (AA 1-140)

The 兔 多克隆 anti-DNAJC2 antibody (ABIN7150549) specifically detects DNAJC2 in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7150549
发货至: 中国
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Quick Overview for DNAJC2 抗体 (AA 1-140) (ABIN7150549)

抗原

See all DNAJC2 抗体
DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This DNAJC2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 1-140

    原理

    DNAJC2 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

    别名

    DNAJC2

    背景

    Background: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at \\\'Lys-119\\\' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5\\\'-GTCAAGC-3\\\'.

    Aliases: AU020218 antibody, DnaJ (Hsp40) homolog subfamily C member 2 antibody, DnaJ homolog subfamily C member 2 antibody, Dnajc2 antibody, DNJC2_HUMAN antibody, M phase phosphoprotein 11 antibody, M-phase phosphoprotein 11 antibody, MGC105894 antibody, MIDA1 antibody, MPHOSPH11 antibody, MPP11 antibody, OTTMUSP00000031226 antibody, ZRF1 antibody, Zrf2 antibody, ZUO1 antibody, Zuotin related factor 1 antibody, Zuotin related factor 2 antibody, Zuotin-related factor 1 antibody

    UniProt

    Q99543

    途径

    Chromatin Binding
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