DFFA 抗体 (Cleaved-Ser118)
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北京 101111
Quick Overview for DFFA 抗体 (Cleaved-Ser118) (ABIN8121030)
抗原
See all DFFA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Ser118
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原理
- DFF45 (Cleaved-Ser118) Antibody
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特异性
- This antibody detects endogenous levels of Human DFF45 (Cleaved-Ser118, protein was cleaved amino acid sequence between117-118 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human DFF45 (Cleaved-Ser118)
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
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别名
- DFF45
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背景
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Synonyms: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD)
Background: function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,
Gene Name: DFFA DFF1 DFF45 H13
Protein Name: DFF45 (Cleaved-Ser118)
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基因ID
- 1676
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UniProt
- O00273
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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